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Human bocavirus infection in children with acute respiratory tract infection in India
Author(s) -
Bharaj Preeti,
Sullender Wayne M.,
Kabra Sushil K.,
Broor Shobha
Publication year - 2010
Publication title -
journal of medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 121
eISSN - 1096-9071
pISSN - 0146-6615
DOI - 10.1002/jmv.21637
Subject(s) - human bocavirus , virology , parvovirus , respiratory tract , virus , nose , respiratory system , respiratory tract infections , medicine , respiratory disease , upper respiratory tract infection , biology , immunology , lung , anatomy
Human bocavirus (HBoV) is a new human parvovirus identified in children with respiratory tract disease. Nasopharyngeal aspirates were collected from 305 children <5 years of age with acute respiratory tract infection from April 2005 to March 2007 and screened for the presence of HBoV by two separate sets of a polymerase chain reaction (PCR) described previously. Twenty‐two (7.2%) children who had acute respiratory infection were found to be positive for HBoV by both sets of PCR. The main clinical symptoms were cough (95%), runny nose (64%), and fever (59%). In two samples, HBoV was identified together with respiratory syncytial virus in one sample and influenza A virus in another. HBoV appeared to have no seasonal distribution and is associated with both upper and lower respiratory tract disease in young children in India. J. Med. Virol. 82: 812–816, 2010. © 2010 Wiley‐Liss, Inc.