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Primary human herpesvirus‐6 associated with an afebrile seizure in a 3‐week‐old infant
Author(s) -
Zerr Danielle M.,
Yeung Laurence C.,
Obrigewitch Rose Mary,
Huang MeeiLi,
Frenkel Lisa M.,
Corey Lawrence
Publication year - 2002
Publication title -
journal of medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 121
eISSN - 1096-9071
pISSN - 0146-6615
DOI - 10.1002/jmv.2156
Subject(s) - human herpesvirus 6 , encephalitis , virology , serology , concomitant , herpesviridae , medicine , polymerase chain reaction , epilepsy , immunocompetence , immunology , viral disease , virus , biology , antibody , immune system , biochemistry , psychiatry , gene
We describe a 3‐week‐old male infant with an afebrile seizure in whom serologic and polymerase chain reaction (PCR) findings support concomitant primary human herpesvirus 6 (HHV‐6) infection. Although HHV‐6 infection has been associated with first‐time febrile seizures and encephalitis in both immunocompetent and immunocompromised hosts, it has not been associated previously with afebrile seizures in healthy infants. This report provides additional evidence of the neuropathogenic potential of HHV‐6. J. Med. Virol. 66:384‐387, 2002. © 2002 Wiley‐Liss, Inc.