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Case report: Hepatitis A preceding Guillain–Barré Syndrome
Author(s) -
Chitambar Shobha D.,
Fadnis Rahul S.,
Joshi Madhuri S.,
Habbu A.,
Bhatia S.G.
Publication year - 2006
Publication title -
journal of medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 121
eISSN - 1096-9071
pISSN - 0146-6615
DOI - 10.1002/jmv.20656
Subject(s) - guillain barre syndrome , virology , medicine , acute hepatitis , hepatitis a virus , genotype , hepatitis , titer , immunology , feces , virus , flaviviridae , viral disease , biology , gene , microbiology and biotechnology , biochemistry
A case of acute hepatitis A with Guillain–Barré Syndrome subtype AMAN (acute motor axonal neuropathy) in a 17‐year‐old male is reported. Serum and cerebrospinal fluid were positive for anti‐hepatitis A virus (HAV) IgM, IgG, and IgA. The onset of the syndrome was evident in week 3 of illness. The remarkably high titers of serum anti‐HAV IgG appeared unique to a hepatitis A patient with the syndrome. Phylogenetic analysis of the HAV genome detected in the serum and feces revealed genotype IIIA, circulating commonly in Pune, western India. J. Med. Virol. 78:1011–1014, 2006. © 2006 Wiley‐Liss, Inc.