Premium
Genetic heterogeneity of hepatitis E virus in Darfur, Sudan, and neighboring Chad
Author(s) -
Nicand Elisabeth,
Armstrong Gregory L.,
Enouf Vincent,
Guthmann Jean Paul,
Guerin JeanPhilippe,
Caron Mélanie,
Nizou Jacques Yves,
Andraghetti Roberta
Publication year - 2005
Publication title -
journal of medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 121
eISSN - 1096-9071
pISSN - 0146-6615
DOI - 10.1002/jmv.20487
Subject(s) - virology , outbreak , hepatitis e virus , genotype , biology , refugee , geography , genetics , gene , archaeology
The within‐outbreak diversity of hepatitis E virus (HEV) was studied during the outbreak of hepatitis E that occurred in Sudan in 2004. Specimens were collected from internally displaced persons living in a Sudanese refugee camp and two camps implanted in Chad. A comparison of the sequences in the ORF2 region of 23 Sudanese isolates and five HEV samples from the two Chadian camps displayed a high similarity (>99.7%) to strains belonging to Genotype 1. But four isolates collected in one of the Chadian camps were close to Genotype 2. Circulation of divergent strains argues for possible multiple sources of infection. J. Med. Virol. 77:519–521, 2005. © 2005 Wiley‐Liss, inc.