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HIV infection and protease genetic diversity in a rural area of the Southern Central African Republic
Author(s) -
Punzi Grazia,
Saracino Annalisa,
Brindicci Gaetano,
Scarabaggio Teresa,
Lagioia Antonella,
Angarano Gioacchino,
Monno Laura
Publication year - 2005
Publication title -
journal of medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 121
eISSN - 1096-9071
pISSN - 0146-6615
DOI - 10.1002/jmv.20476
Subject(s) - virology , genetic diversity , diversity (politics) , human immunodeficiency virus (hiv) , protease , biology , geography , medicine , environmental health , political science , enzyme , population , biochemistry , law
Thirty‐eight of 175 (21.7%) consecutive women of childbearing age from a rural area near Bangassou were tested HIV‐positive. Ten protease and two protease/reverse transcriptase sequences (31.5% samples) were obtained. Eight sequences clustered into subtype J, A, G; two sequences were 13_cpx recombinant forms and two were indeterminate. The high proportion of HIV found suggests a recent outbreak of diversified HIV strains. J. Med. Virol. 77:457–459, 2005. © 2005 Wiley‐Liss, inc.