HIV infection and protease genetic diversity in a rural area of the Southern Central African Republic | Zendy

Punzi Grazia | Zendy; Saracino Annalisa | Zendy; Brindicci Gaetano | Zendy; Scarabaggio Teresa | Zendy; Lagioia Antonella | Zendy; Angarano Gioacchino | Zendy; Monno Laura | Zendy

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HIV infection and protease genetic diversity in a rural area of the Southern Central African Republic

Author(s) -

Punzi Grazia,

Saracino Annalisa,

Brindicci Gaetano,

Scarabaggio Teresa,

Lagioia Antonella,

Angarano Gioacchino,

Monno Laura

Publication year - 2005

Publication title -

journal of medical virology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.782

H-Index - 121

eISSN - 1096-9071

pISSN - 0146-6615

DOI - 10.1002/jmv.20476

Subject(s) - virology , genetic diversity , diversity (politics) , human immunodeficiency virus (hiv) , protease , biology , geography , medicine , environmental health , political science , enzyme , population , biochemistry , law

Thirty‐eight of 175 (21.7%) consecutive women of childbearing age from a rural area near Bangassou were tested HIV‐positive. Ten protease and two protease/reverse transcriptase sequences (31.5% samples) were obtained. Eight sequences clustered into subtype J, A, G; two sequences were 13_cpx recombinant forms and two were indeterminate. The high proportion of HIV found suggests a recent outbreak of diversified HIV strains. J. Med. Virol. 77:457–459, 2005. © 2005 Wiley‐Liss, inc.

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