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Retrospective, longitudinal analysis of serum human herpesvirus‐8 viral DNA load in AIDS‐related kaposi's sarcoma patients before and after diagnosis
Author(s) -
Polstra Abeltje M.,
Cornelissen Marion,
Goudsmit Jaap,
van der Kuyl Antoinette C.
Publication year - 2004
Publication title -
journal of medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 121
eISSN - 1096-9071
pISSN - 0146-6615
DOI - 10.1002/jmv.20192
Subject(s) - sarcoma , viremia , virology , viral load , viral disease , kaposi's sarcoma , human herpesvirus , medicine , virus , herpesviridae , disease , immunology , pathology
Human herpesvirus 8 (HHV‐8) is detected more often in patients progressing towards Kaposi's sarcoma (KS) than in patients who do not develop the disease, suggesting that the level of viremia might be associated with Kaposi's sarcoma disease and progression. Longitudinal serum samples from 19 AIDS‐Kaposi's sarcoma patients, ranging from 2 years before KS till 2 years after KS diagnosis were tested. No correlation was found between viral load and progression to KS, or disease stage. J. Med. Virol. 74:390–396, 2004. © 2004 Wiley‐Liss, Inc.