Premium
Adenovirus mixture isolated from the brain of an AIDS patient with encephalitis
Author(s) -
Schnurr David,
Bollen Andrew,
CrawfordMiksza Leta,
Dondero Marge E.,
Yagi Shigeo
Publication year - 1995
Publication title -
journal of medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 121
eISSN - 1096-9071
pISSN - 0146-6615
DOI - 10.1002/jmv.1890470210
Subject(s) - virology , encephalitis , restriction enzyme , mastadenovirus , serotype , adenoviridae , immunofluorescence , viral encephalitis , biology , virus , antibody , recombinant dna , immunology , gene , genetics
A mixture of adenoviruses 31 and 49 was isolated from the brain of an AIDS patient with encephalitis. Adenovirus hexon protein was detected in neurons by indirect immunoflourescence. By restriction endonuclease analysis both adenovirus 31 and 49 were shown to be new genotypes. This is the first report of the isolation of a mixture of adenoviruses from adenovirus encephalitis and the first association of adenovirus 49, a new candidate serotype, with encephalitis. © 1995 WiIey‐Liss, Inc.