Premium
Sequence comparison of echovirus type 30 isolates to other enteroviruses in the 5′noncoding region
Author(s) -
Diedrich Sabine,
Driesel Gerhard,
Schreier Eckart
Publication year - 1995
Publication title -
journal of medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 121
eISSN - 1096-9071
pISSN - 0146-6615
DOI - 10.1002/jmv.1890460212
Subject(s) - echovirus , enterovirus , virology , coxsackievirus , biology , homology (biology) , polymerase chain reaction , nucleic acid sequence , enterovirus infections , virus , sequence analysis , genetics , gene
The genetic relationship between echovirus type 30 (E30) isolates were characterised by means of amplification of a part of the 5′noncoding region by polymerase chain reaction and direct sequencing. Later, the E30 sequences were compared with other enteroviruses. Homology between recent clinical E30 isolates from different years exceeds 98% at the nucleotide level. Comparing the E30 sequence with other enteroviruses, homology varied between 68% (coxsackievirus A24) and 93% (coxsackievirus B3). E30 appeared to have coxsackie B‐like characteristics in this genomic part. It is considered that E30 and coxsackie B viruses belong to the same enterovirus subgroup. © 1995 Wiley‐Liss, Inc.