Detection of IgA class antibody to hepatitis E virus in serum samples from patients with hepatitis E virus infection | Zendy

Chau Kurt H. | Zendy; Dawson George J. | Zendy; Bile Khalif M. | Zendy; Magnius Lars O. | Zendy; Sjogren Maria H. | Zendy; Mushahwar Isa K. | Zendy

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Detection of IgA class antibody to hepatitis E virus in serum samples from patients with hepatitis E virus infection

Author(s) -

Chau Kurt H.,

Dawson George J.,

Bile Khalif M.,

Magnius Lars O.,

Sjogren Maria H.,

Mushahwar Isa K.

Publication year - 1993

Publication title -

journal of medical virology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.782

H-Index - 121

eISSN - 1096-9071

pISSN - 0146-6615

DOI - 10.1002/jmv.1890400414

Subject(s) - virology , virus , antibody , hepatitis a virus , hepatitis e virus , hepatitis , medicine , biology , immunology , gene , genotype , biochemistry

A newly developed assay for IgA class antibody to hepatitis E virus (IgA anti‐HEV) was used to study 145 serum samples collected during an outbreak of an enterically transmitted hepatitis that occurred in 3 villages in the lower Shebeli region of Southern Somalia between January, 1988 and November, 1989. A total of 52.4% of the afflicted patients were found positive for IgA anti‐HEV, and 73.1% of these were also positive for IgM. Both antibodies disappeared during the convalescence period. Similar results were also seen in serum obtained from sporadic cases of acute waterborne hepatitis in Pakistan. © 1993 Wiley‐Liss, Inc.

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