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Seroepidemiology of cytomegalovirus infection among children between the ages of 4 and 12 years in Taiwan
Author(s) -
Shen ChenYang,
Chang WhiWen,
Chang ShuFen,
Chao MaioFen,
Huang EngShang,
Wu ChenWen
Publication year - 1992
Publication title -
journal of medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 121
eISSN - 1096-9071
pISSN - 0146-6615
DOI - 10.1002/jmv.1890370113
Subject(s) - cytomegalovirus , socioeconomic status , medicine , transmission (telecommunications) , immunology , serology , logistic regression , viral disease , demography , virology , antibody , herpesviridae , virus , environmental health , population , sociology , electrical engineering , engineering
To determine risk factors responsible for primary cytomegalovirus (CMV) infection in Taiwan, samples of blood for antibody to CMV were obtained from 362 children aged 4 to 12 years: 58% were found to be positive for anti‐CMV IgG antibody. Logistic regression analysis showed that seropositivity correlated with age, method of delivery, duration of breast feeding, and younger age of mother. Neither socioeconomic status nor crowded living conditions showed significant correlation with CMV seropositivity. Primary CMV infection in Taiwan appears to be less related to socioeconomic status shown in western countries, and, since the majority of pregnant women were seropositive in Taiwan, two of the major sources of primary CMV transmission are infected breast milk and the infected genital tract. © 1992 Wiley‐Liss, Inc.