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Measles virus specific antibody in infants in a highly vaccinated society
Author(s) -
Chui Linda WL.,
Marusyk Raymond G.,
Pabst Henry F.
Publication year - 1991
Publication title -
journal of medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 121
eISSN - 1096-9071
pISSN - 0146-6615
DOI - 10.1002/jmv.1890330311
Subject(s) - measles , virology , measles virus , neutralizing antibody , neutralization , antibody , virus , immunity , population , medicine , biology , hemagglutination assay , immunology , vaccination , titer , immune system , environmental health
Measles virus specific antibody levels were measured in infants from 2 to 12 months of age. The sera were tested by hemagglutination‐inhibition (HI), neutralization (NT), and enzyme immunoas‐say (EIA) methods. The results of this study indicate that in the population examined, infants at an early age have very low or no immunity of maternal origin to measles virus‐93% of the infants were without detectable neutralizing antibody (NT liter ≤10) at 6 months of age, and by the end of the first year of life 100% had no neutralizing antibody.