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Inhibition of rate of tumour growth in rodent species by inoculation of herpesviruses and encephalomyocarditis virus
Author(s) -
Cowan M.,
Davies J.,
Brookes K.,
Billstrom M.,
McLeish P.,
Buchan A.,
Skinner G. R. B.
Publication year - 1990
Publication title -
journal of medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 121
eISSN - 1096-9071
pISSN - 0146-6615
DOI - 10.1002/jmv.1890300313
Subject(s) - virology , inoculation , virus , biology , immunology
Inoculation of herpesviruses and encephalomyocarditis virus into subcutaneous tumours in hamsters and mice reduced the rate of tumour growth compared to untreated tumours or secondary tumours which had arisen following surgical excision of the primary tumour; in addition, survival times were increased in animals whose tumours were inoculated with virus. It is suggested that the role of virus in the modification of tumour growth merits further exploration.