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A new genome type of adenovirus 3 associated with severe lower acute respiratory infection in children
Author(s) -
Kajon Adriana E.,
Murtagh Patricia,
Franco Susana Garcia,
Freire Maria Cecilia,
Weissenbacher Mercedes C.,
Zorzópulos Jorge
Publication year - 1990
Publication title -
journal of medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 121
eISSN - 1096-9071
pISSN - 0146-6615
DOI - 10.1002/jmv.1890300116
Subject(s) - mastadenovirus , serotype , virology , genome , adenoviridae , biology , respiratory system , restriction enzyme , respiratory infection , respiratory disease , virus , lung , gene , medicine , genetics , genetic enhancement , anatomy
Adenovirus 3 was found associated with ten cases of infantile lower acute respiratory infection in patients aged 2–18 months. Of these, five had a fatal outcome, with severe lung damage. Restriction enzyme analysis with Bam HI, Bcl I, BgI II, Bst E II, Hind III, Sal I, Sma I, Xba I, and Xho I revealed the presence of the same genome type in all ten specimens. The genomic variant was different from those previously reported for serotype 3 and therefore was tentatively denominated 3f.