A new genome type of adenovirus 3 associated with severe lower acute respiratory infection in children | Zendy

Kajon Adriana E. | Zendy; Murtagh Patricia | Zendy; Franco Susana Garcia | Zendy; Freire Maria Cecilia | Zendy; Weissenbacher Mercedes C. | Zendy; Zorzópulos Jorge | Zendy

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A new genome type of adenovirus 3 associated with severe lower acute respiratory infection in children

Author(s) -

Kajon Adriana E.,

Murtagh Patricia,

Franco Susana Garcia,

Freire Maria Cecilia,

Weissenbacher Mercedes C.,

Zorzópulos Jorge

Publication year - 1990

Publication title -

journal of medical virology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.782

H-Index - 121

eISSN - 1096-9071

pISSN - 0146-6615

DOI - 10.1002/jmv.1890300116

Subject(s) - mastadenovirus , serotype , virology , genome , adenoviridae , biology , respiratory system , restriction enzyme , respiratory infection , respiratory disease , virus , lung , gene , medicine , genetics , genetic enhancement , anatomy

Adenovirus 3 was found associated with ten cases of infantile lower acute respiratory infection in patients aged 2–18 months. Of these, five had a fatal outcome, with severe lung damage. Restriction enzyme analysis with Bam HI, Bcl I, BgI II, Bst E II, Hind III, Sal I, Sma I, Xba I, and Xho I revealed the presence of the same genome type in all ten specimens. The genomic variant was different from those previously reported for serotype 3 and therefore was tentatively denominated 3f.

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