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Detection of anti rotavirus coproantibodies by immunoblotting technique
Author(s) -
Ushijima Hiroshi,
Shinozaki Tatsuhiko,
Kitamura Takashi
Publication year - 1989
Publication title -
journal of medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 121
eISSN - 1096-9071
pISSN - 0146-6615
DOI - 10.1002/jmv.1890290209
Subject(s) - virology , rotavirus , reoviridae , rotavirus infections , virus , biology
Abstract IgA and IgG coproantibodies to individual simian rotavirus (SA 11) structural polypeptides were detected in healthy infants in nursery homes. The number of immunoblottable peptides differed from individual to individual. Coproantibodies were also detected at the convalescent stage of rotavirus infection in two patients but not during the acute stage. This method is useful for confirming the diagnosis of rotavirus infection serologically without the need for paired sera.