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Outbreak of poliomyelitis in south africa investigated by oligonucleotide mapping
Author(s) -
Tsilimigras C. W. A.,
Rossouw E.,
Schoub B. D.
Publication year - 1989
Publication title -
journal of medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 121
eISSN - 1096-9071
pISSN - 0146-6615
DOI - 10.1002/jmv.1890280112
Subject(s) - outbreak , virology , poliomyelitis , virus , biology , strain (injury) , anatomy
An outbreak of paralytic poliomyelitis, due to polio type 1 virus, occurred in the Gazankulu region of the Transvaal in the Republic of South Africa in 1982. Thirty‐four different isolates from this epidemic were characterized by oligonucleotide mapping. None of the isolates were shown to be vaccine related. Results suggest the existence of a number of apparently different wild‐type viruses present in the area. The introduction of a single wild‐type strain could not be clearly demonstrated. These findings have important implications for the management and control of future outbreaks.