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Seroepidemiological survey of the prevalence of antibodies to a strain of human calicivirus
Author(s) -
Cubitt W. D.,
McSwiggan D. A.
Publication year - 1987
Publication title -
journal of medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 121
eISSN - 1096-9071
pISSN - 0146-6615
DOI - 10.1002/jmv.1890210408
Subject(s) - calicivirus , antibody , feline calicivirus , virology , population , immune system , strain (injury) , incidence (geometry) , serology , medicine , immunology , biology , virus , physics , environmental health , optics
Batches of pooled immune globulins and sera were tested by immune electron microscopy (IEM) for the presence of antibodies to a strain of human calicivirus (HCV, UK1). The results show that this strain of HCV is prevalent throughout many parts of the world anti that the majority of the population experience infection by the age of 12 years. The survey carried out in the United Kingdom indicates that the presence of maternal antibody correlates with some degree of protection during the first few weeks of life; the peak incidence of cases and acquisition of antibody occur between 3 months and 6 years. Tests on sera from Japan show a similar pattern of acquisition of antibodies and demonstrate that infection with more than one strain of HCV commonly occurs during childhood.