Thermostabilization of Inoue‐Melnick Virus by Salt

Inoue‐Melnick virus (IMV) was stabilized to thermal inactivation at 50°C by 1 M Na 2 S0 4 but not by 1 M MgC1 2 , 1 M MgS0 4 , 2 M NaC1, and 2 M KCl. The latter salts enhanced the inactivation over that in distilled water. Na2S04 stabilized IMV at 1 M concentration but enhanced inactivation at 0.1 M. Three types of IMV were stabilized by 1 M Na 2 S0 4 at 50°C to almost the same degree. The pattern of the thermostabilization of IMV by salts was similar to that of herpes simplex virus; however, the degree of its stabilization was lower with prolonged heating.