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Immune responses to late booster doses of hepatitis B vaccine
Author(s) -
Jilg Wolfgang,
Schmidt Marion,
Deinhardt Friedrich
Publication year - 1985
Publication title -
journal of medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 121
eISSN - 1096-9071
pISSN - 0146-6615
DOI - 10.1002/jmv.1890170306
Subject(s) - booster dose , immune system , hepatitis b vaccine , virology , booster (rocketry) , hepatitis b , medicine , immunology , vaccination , hepatitis , hepatitis a vaccine , hepatitis b virus , immunization , virus , hbsag , physics , astronomy
Abstract Nineteen healthy young adults were vaccinated with plasma‐derived hepatitis B vaccine at months 0, 1, and 12, and their immune responses were compared to those of a similar group of 20 vaccinees immunized at months 0, 1, and 6. Late booster injections at 12 months produced nearly fivefold higher geometric mean anti‐HBs levels than those of the control group. The higher anti‐HBs values may lead to longer persistence of anti‐HBs and thus to longer protection against hepatitis B.