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Relative frequency of human rotavirus subgroups 1 and 2 in Japanese children with acute gastroenteritis
Author(s) -
Nakagomi Osamu,
Nakagomi Toyoko,
Oyamada Hajime,
Suto Tsunehisa
Publication year - 1985
Publication title -
journal of medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 121
eISSN - 1096-9071
pISSN - 0146-6615
DOI - 10.1002/jmv.1890170105
Subject(s) - rotavirus , virology , acute gastroenteritis , subgroup analysis , capsid , diarrhoeal disease , serotype , medicine , biology , virus , diarrhea , gastroenterology , meta analysis
Recently developed monoclonal antibodies against the 42,000‐dalton major inner capsid protein were used in an enzyme immunoassay to subgroup a total of 156 rotavirus specimens obtained from Japanese infants and young children with acute gastroenteritis during the period between December 1981 and April 1983. Only 2 specimens (1.3%) were identified as subgroup 1, whereas 154 specimens (98.7%) were identified as subgroup 2. The percentage of subgroup 2 rotaviruses obtained in this study was the highest among similar studies thus far performed in different areas of the world. One of the subgroup 1 isolates had fast‐moving 10th and 11th gene segments (the “long” pattern) typical of the subgroup 2 human rotaviruses.