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Factors associated with primary cytomegalovirus infection during pregnancy
Author(s) -
Stagno Sergio,
Cloud Gretchen,
Pass Robert F.,
Britt William J.,
Alford Charles A.
Publication year - 1984
Publication title -
journal of medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 121
eISSN - 1096-9071
pISSN - 0146-6615
DOI - 10.1002/jmv.1890130405
Subject(s) - pregnancy , cytomegalovirus , medicine , logistic regression , cytomegalovirus infections , gestation , cytomegalovirus infection , obstetrics , rubella virus , socioeconomic status , rubella , demography , pediatrics , immunology , viral disease , herpesviridae , human immunodeficiency virus (hiv) , human cytomegalovirus , virus , vaccination , biology , environmental health , measles , population , sociology , genetics
We compared a group of 40 susceptible pregnant women who acquired CMV during gestation with a group of 86 women of similar race and socioeconomic background who remained seronegative to define factors associated with the risk of CMV infection during pregnancy. A logistic regression model using a stepwise procedure showed that a positive statistically significant correlation occurred with the age of the mother, the father's high‐intensity contact with young children, and children living at home. A negative correlation occurred with mother's high‐risk intensity contact with children outside the home. This study underlines the possibility that pregnant women may acquire CMV infection introduced into the household by their young children and husbands, a phenomenon that is reminiscent of rubella infection.