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Disseminated neonatal echovirus 11 disease following antenatal maternal infection with a virus‐positive cervix and virus‐negative gastrointestinal tract
Author(s) -
Reyes Milagros P.,
Ostrea Enrique M.,
Roskamp Jacqueline,
Lerner A. Martin
Publication year - 1983
Publication title -
journal of medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 121
eISSN - 1096-9071
pISSN - 0146-6615
DOI - 10.1002/jmv.1890120210
Subject(s) - echovirus , medicine , cervix , virology , chills , enterovirus , virus , immunology , cancer
An infant girl was born apparently well one week after her mother had had a mild illness with chills, fever, and diarrhea. On the third day of life, the infant became ill and died four days later with necrotizing hepatitis. On the same day, echovirus type 11 was recovered from the throat, rectum, and buffy coat of the infant and from the cervix of the mother. At this time, the mother had an IgM neutralizing antibody titer to echovirus type 11 of 1:128, but no IgG antibodies. The infant had no echovirus type 11 antibodies. The virus was also isolated from the baby's liver and adrenal at autopsy. These findings raise the possibility of enterovirus infection at delivery from a contaminated cervix.