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Cocirculation of different rotavirus strains in a local outbreak of infantile gastroenteritis: Monitoring by rapid and sensitive nucleic acid analysis
Author(s) -
Follett Edward A. C.,
Desselberger Ulrich
Publication year - 1983
Publication title -
journal of medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 121
eISSN - 1096-9071
pISSN - 0146-6615
DOI - 10.1002/jmv.1890110106
Subject(s) - outbreak , virology , nucleic acid , rna , rotavirus , serology , biology , acute gastroenteritis , staining , silver stain , virus , microbiology and biotechnology , genetics , antibody , gene
Rotaviruses isolated from 22 patients during a local outbreak of infantile gastroenteritis in October/November 1981 were genotyped by establishing their RNA migration patterns on polyacrylamide gels. A highly sensitive silver staining procedure was used to visualize the RNAs. It was found that strains with at least four different RNA patterns cocirculated and also showed serological differences.