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Antibodies to gastroenteritis viruses in cystic fibrosis patients
Author(s) -
Cukor George,
Blacklow Neil R.,
Braverman Lewis E.
Publication year - 1982
Publication title -
journal of medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 121
eISSN - 1096-9071
pISSN - 0146-6615
DOI - 10.1002/jmv.1890090302
Subject(s) - cystic fibrosis , virology , antibody , rotavirus , infectivity , virus , biology , viral disease , medicine , immunology
Infectivity of certain enteric viruses including rotavirus is profoundly affected by proteolytic enzymes. To test whether cystic fibrosis patients, possessing chronically decreased levels of pancreatic enzymes, show altered susceptibility to gastroenteritis viruses, we examined sera from patients and controls for antibodies to two major pathogens. In cystic fibrosis patients, normal rotavirus antibody levels were found and Norwalk virus antibody prevalence was unchanged.