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The 33‐ to 39‐nm virus‐like particles, tentatively designated as sapporo agent, associated with an outbreak of acute gastroenteritis
Author(s) -
Kogasaka Ryoichi,
Nakamura Shinichi,
Chiba Shunzo,
Sakuma Yasuhiko,
Terashima Hideyuki,
Yokoyama Takashi,
Nakao Tooru
Publication year - 1981
Publication title -
journal of medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 121
eISSN - 1096-9071
pISSN - 0146-6615
DOI - 10.1002/jmv.1890080305
Subject(s) - outbreak , acute gastroenteritis , feces , virology , diarrhea , virus , infectious agent , norwalk virus , medicine , microbiology and biotechnology , biology , norovirus , disease
An outbreak of nonbacterial gastroenteritis occurred in an orphanage in December 1979. Of 54 residents, 43 were affected with acute gastroenteritis. Diarrhea was the commonest symptom. The 33‐ to 39‐nm virus‐like particles, tentatively designated as Sapporo agent, were detected in 17 (48.6%) of the patients' 35 fecal specimens. Morphologically, it was difficult to distinguish the Sapporo agent from other agents without geometrical pattern on the surface. Antigenically, the Sapporo agent related to the Otofuke agent detected in an outbreak of the institution for mentally retarded adults and also to the SRV '76 detected in familial cases of infectious gastroenteritis. The Sapporo agent might belong to a new group of those gastroenteritis viruses which were larger in size than the Norwalk virus group.