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A reverse passive haemagglutination test for the detection of respiratory syncytial virus in nasal secretions from infants
Author(s) -
Cranage M.P.,
Stott E.J.,
Nagington J.,
Coombs R.R.A.
Publication year - 1981
Publication title -
journal of medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 121
eISSN - 1096-9071
pISSN - 0146-6615
DOI - 10.1002/jmv.1890080301
Subject(s) - virology , virus , hemagglutination , respiratory system , paramyxoviridae , staining , medicine , antibody , biology , immunology , viral disease , pathology
A reverse passive haemagglutination (RPH) test has been developed for the detection of respiratory syncytial (RS) virus in nasal secretions, taken from infants with acute respiratory illness. In the final form of the procedure, RS virus was detected in 24 of 25 samples positive for RS virus by tissue culture and/or fluorescence antibody staining and in two samples negative for RS virus by these techniques. The simplicity of the technique and the rapidity with which it may be performed together with its apparently high degree of sensitivity should make RPH useful in the rapid diagnosis of RS virus.