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Characterization of candidate adenovirus 37 by SDS‐polyacrylamide gel electrophoresis of virion pplypeptides and DNA restriction site mapping
Author(s) -
Wadell Göran,
Sundell Gunnar,
De Jong Jan C.
Publication year - 1981
Publication title -
journal of medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 121
eISSN - 1096-9071
pISSN - 0146-6615
DOI - 10.1002/jmv.1890070205
Subject(s) - restriction enzyme , virology , biology , polyacrylamide gel electrophoresis , keratoconjunctivitis , microbiology and biotechnology , serotype , gel electrophoresis , mastadenovirus , dna , genome , adenoviridae , genetics , gene , recombinant dna , enzyme , biochemistry
A new human adenovirus has been isolated from patients with keratoconjunctivitis and/or genital infection since 1976. This adenovirus, designated candidate adenovirus 37 (Ad 37) is serologically distinct but related to Ad 10, 13, 19, and 30 (see the accompanying paper by de Jong et al). SDS‐Polyacrylamide gel electrophoresis of Ad 37 virion polypeptides showed that this adenovirus is a member of subgroup D. DNA restriction endonuclease analysis of DNA from Ad 37 and related serotypes belonging to subgroup D showed that Ad 37 is a new genome type belonging to subgroup D but clearly distinct from the 20 serotypes classified into this subgroup.