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Serological survey to detect subclinicai junían virus infection in laboratory personnel
Author(s) -
Weissenbacher M. C.,
Edelmuth E.,
Frigerio M. J.,
Coto C. E.,
De Guerrero L. B.
Publication year - 1980
Publication title -
journal of medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 121
eISSN - 1096-9071
pISSN - 0146-6615
DOI - 10.1002/jmv.1890060305
Subject(s) - subclinical infection , serology , virology , virus , medicine , antibody , vero cell , etiology , neutralizing antibody , immunology
Serological survey for detecting subclinical infections with Junín virus, the etiological agent of Argentine hemorrhagic fever, was carried out in a group of 107 individuals working in laboratories where this virus was handled, The group was divided into high risk and low risk personnel according to the degree of exposure to the virus. Neutralizing tests were performed in Vero cell cultures to detect circulating antibodies. Results were evaluated comparatively with those obtained in a previous survey. This study shows that among high risk personnel three out of 52 developed neutralizing antibodies (NA) against Junín virus; one of them had a mild clinical illness, and the other two showed no overt disease during this period. No one among the low risk group developed NA against Junín virus.