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Hepatitis b surface antigen (hb s ag) in peritoneal fluid of hb s ag carriers undergoing peritoneal dialysis
Author(s) -
Salo Richard J.,
Salo Ann A.,
Fahlberg Wilson J.,
Ellzey Joanne T.
Publication year - 1980
Publication title -
journal of medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 121
eISSN - 1096-9071
pISSN - 0146-6615
DOI - 10.1002/jmv.1890060105
Subject(s) - hbsag , peritoneal dialysis , medicine , ascitic fluid , virology , antigen , immunology , hepatitis b virus , ascites , virus
Samples of ascitic fluid and outflow dialysate were collected from HB s Ag carriers undergoing peritoneal dialysis and tested for HB s Ag by solid‐phase radioimmunoassy. The surface antigen was detected in every sample from HB s Ag carriers. This finding was not dependent upon the presence of occult blood in the sample. Surface antigen particles and possibly Dane particles were also observed in HB s Ag‐positive samples by immunoelectron microscopy. These results identify the outflow dialysate of HB s Ag carriers undergoing peritoneal dialysis as a potential source of hepatitis B virus transmission.