Multiple buoyant densities of hepatitis A virus in cesium chloride gradients | Zendy

Bradley Daniel W. | Zendy; McCaustland Karen A. | Zendy; Schreeder Marshall T. | Zendy; Cook E. H. | Zendy; Gravelle Clifton R. | Zendy; Maynard James E. | Zendy

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Multiple buoyant densities of hepatitis A virus in cesium chloride gradients

Author(s) -

Bradley Daniel W.,

McCaustland Karen A.,

Schreeder Marshall T.,

Cook E. H.,

Gravelle Clifton R.,

Maynard James E.

Publication year - 1977

Publication title -

journal of medical virology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.782

H-Index - 121

eISSN - 1096-9071

pISSN - 0146-6615

DOI - 10.1002/jmv.1890010309

Subject(s) - virology , hepatitis a virus , buoyant density , virus , caesium , chloride , biology , chemistry , inorganic chemistry , organic chemistry

Hepatitis A virus (HAV) recovered from stools of human cases of hepatitis A and from stools of chimpanzees experimentally infected with HAV was shown to possess multiple buoyant densities in CsCl gradients. The greatest proportion of HAV was most frequently found at a buoyant density of 1.32–1.34 g/cm 3 , however, large proportions of HAV were also frequently found at higher densities, including 1.36–1.37, 1.40–1.42, and 1.45–1.48 g/cm 3 . These findings are consistent with the notion that HAV may be a parvovirus.

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