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Multiple buoyant densities of hepatitis A virus in cesium chloride gradients
Author(s) -
Bradley Daniel W.,
McCaustland Karen A.,
Schreeder Marshall T.,
Cook E. H.,
Gravelle Clifton R.,
Maynard James E.
Publication year - 1977
Publication title -
journal of medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 121
eISSN - 1096-9071
pISSN - 0146-6615
DOI - 10.1002/jmv.1890010309
Subject(s) - virology , hepatitis a virus , buoyant density , virus , caesium , chloride , biology , chemistry , inorganic chemistry , organic chemistry
Hepatitis A virus (HAV) recovered from stools of human cases of hepatitis A and from stools of chimpanzees experimentally infected with HAV was shown to possess multiple buoyant densities in CsCl gradients. The greatest proportion of HAV was most frequently found at a buoyant density of 1.32–1.34 g/cm 3 , however, large proportions of HAV were also frequently found at higher densities, including 1.36–1.37, 1.40–1.42, and 1.45–1.48 g/cm 3 . These findings are consistent with the notion that HAV may be a parvovirus.