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Comparison of the seroprevalence of human metapneumovirus and human respiratory syncytial virus
Author(s) -
Ebihara Takashi,
Endo Rika,
Kikuta Hideaki,
Ishiguro Nobuhisa,
Ishiko Hiroaki,
Kobayashi Kunihiko
Publication year - 2004
Publication title -
journal of medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 121
eISSN - 1096-9071
pISSN - 0146-6615
DOI - 10.1002/jmv.10572
Subject(s) - human metapneumovirus , seroprevalence , bronchiolitis , virology , paramyxoviridae , virus , pneumovirinae , mononegavirales , metapneumovirus , pneumovirus , pneumonia , antibody , respiratory system , respiratory tract infections , immunofluorescence , serology , respiratory tract , lower respiratory tract infection , biology , medicine , immunology , viral disease
Human metapneumovirus (hMPV) is a virus that induces human respiratory syncytial virus (hRSV)‐like illnesses, ranging from upper respiratory tract infection to severe bronchiolitis and pneumonia. The 100 serum samples from children aged 1 month to 5 years were tested for the presence of hMPV and hRSV antibodies using an indirect immunofluorescence assay and a neutralizing‐antibody assay, respectively. The seroprevalence of hMPV was significantly lower than that of hRSV in children over 4‐months‐old (43% vs. 60%, P < 0.025), and the difference was particularly notable between the ages of 4 months and 1 year (11% vs. 48%, P = 0.006). The results suggest that primary infection with hMPV occurs somewhat later than that with hRSV. J. Med. Virol. 72:304–306, 2004. © 2004 Wiley‐Liss, Inc.
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