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IL‐10 gene polymorphism and herpesvirus infections
Author(s) -
Hurme M.,
Haanpää M.,
Nurmikko T.,
Wang X.Y.,
Virta M.,
Pessi T.,
Kilpinen S.,
Hulkkonen J.,
Helminen M.
Publication year - 2003
Publication title -
journal of medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 121
eISSN - 1096-9071
pISSN - 0146-6615
DOI - 10.1002/jmv.10320
Subject(s) - virology , gene , biology , herpesviridae , polymorphism (computer science) , genetics , virus , genotype , viral disease
Abstract Genetics has an important role in resistance to various infections and it also may modify the clinical picture of an infectious disease. Here, we briefly review our recent data demonstrating that the polymorphism of the IL‐10 gene is associated with resistance to some common herpesviruses and, additionally, that this same gene is involved in the regulation of the severity of the infection and in the reactivation process. J. Med. Virol. 70:S48–S50, 2003. © 2003 Wiley‐Liss, Inc.