z-logo
Premium
Characterization and application of a self‐aspirating electrospray source with pneumatic‐assisted ionization
Author(s) -
Yu Q.,
Zhang J.,
Ni K.,
Qian X.,
Wang X.
Publication year - 2017
Publication title -
journal of mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 1076-5174
DOI - 10.1002/jms.3907
Subject(s) - chemistry , extractive electrospray ionization , desorption electrospray ionization , ion source , ambient ionization , mass spectrometry , electrospray ionization , electrospray , analytical chemistry (journal) , characterization (materials science) , ionization , chromatography , direct electron ionization liquid chromatography–mass spectrometry interface , desorption , ion , sample preparation in mass spectrometry , chemical ionization , nanotechnology , thermal ionization mass spectrometry , materials science , organic chemistry , adsorption
A single gas‐assisted electrospray ion source developed for ambient mass spectrometry is introduced in this paper. Simultaneous self‐aspiration and electrospray could be achieved by using a constant sheath gas flow supplied from a mini air pump. A gas dynamic study of the spray module is carried out for structural optimization. The entire device exhibits a simplified design and has been systematically characterized through both simulated and experimental investigations. According to the results, the ion source exhibited satisfactory stability and the ability for quantitative operation in routine electrospray ionization mass spectrometry. Furthermore, the ion source can be operated as a desorption electrospray ionization source to perform direct desorption/ionization of the solid samples. The versatile source described here appears to provide a practical approach to perform ambient mass spectrometry analysis with unrestricted sampling operation, and the extensive gas dynamic studies together with the experimental characterization are believed to be helpful in building self‐aspirating spray devices. Copyright © 2017 John Wiley & Sons, Ltd.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here