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A study of enhanced ion formation from metal‐semiconductor complexes in atmospheric pressure laser desorption/ionization mass spectrometry
Author(s) -
Silina Yuliya E.,
HerbeckEngel Petra,
Koch Marcus
Publication year - 2017
Publication title -
journal of mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 1076-5174
DOI - 10.1002/jms.3898
Subject(s) - chemistry , mass spectrometry , analytical chemistry (journal) , matrix assisted laser desorption electrospray ionization , desorption , ambient ionization , atmospheric pressure laser ionization , soft laser desorption , semiconductor , ion mobility spectrometry , substrate (aquarium) , ionization , matrix assisted laser desorption/ionization , ion , electron ionization , chromatography , optoelectronics , adsorption , materials science , organic chemistry , oceanography , geology
The study of the key parameters impacted surface‐assisted laser desorption/ionization‐mass spectrometry is of broad interest. In previous studies, it has been shown that surface‐assisted laser desorption/ionization‐mass spectrometry is a complex process depending on multiple factors. In the presented study, we showed that neither porosity, light absorbance nor surface hydrophobicity alone influence the enhancement phenomena observed from the hybrid metal‐semiconductor complexes versus individual targets, but small changes in the analyte attaching to the target significantly affect laser desorption ionization‐efficiency. By means of Raman spectroscopy and scanning electron microscopy, it was revealed that the formation of an amorphous analyte layer after drying on a solid substrate was essential for the enhanced laser desorption ionization‐signal observed from the hybrid metal‐semiconductor targets, and the crystallization properties of the analyte appeared as a function of the substrate. Obtained results were used for the screening of regular and lactose‐free milk samples through the hybrid metal‐semiconductor target. Copyright © 2016 John Wiley & Sons, Ltd.