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Electrospray ionization mass spectrometric detection of low polar compounds by adding NaAuCl 4
Author(s) -
Moriwaki Hiroshi
Publication year - 2016
Publication title -
journal of mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 1076-5174
DOI - 10.1002/jms.3822
Subject(s) - chemistry , pyrene , perylene , electrospray ionization , mass spectrometry , electrospray , electron ionization , chemical ionization , chromatography , polar , analytical chemistry (journal) , ion , ionization , organic chemistry , molecule , astronomy , physics
Liquid chromatography electrospray ionization mass spectrometry (LC/ESI/MS) has been widely used for various analyses. However, it is difficult to use LC/ESI/MS for the analysis of low polar compounds, such as polycyclic aromatic hydrocarbons. It is well known that AuCl 4 − ion decomposes to AuCl 3 by heating, and AuCl 3 is a strong π‐electrophilic Lewis acid. Low polar compounds (pyrene, benzo[ a ]pyrene, perylene, benzo[ ghi ]perylene, dibenzothiophene and p ‐dimethoxybenzene) were detected by ESI/MS in the positive ion mode by adding NaAuCl 4 . The low polar compound interacts with AuCl 3 formed at the ESI interface, and undergoes electron transfer to AuCl 3 . The radical cation of the low polar compound was then detected by MS. In addition, the LC/ESI/MS determination of polycyclic aromatic hydrocarbons by the post‐column addition of NaAuCl 4 was studied. © 2016 The Authors Journal of Mass Spectrometry Published by John Wiley & Sons Ltd