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Effects of different alkali metal ions on the cationization of poly(ethylene glycol)s in matrix‐assisted laser desorption/ionization mass spectrometry: a new selectivity parameter
Author(s) -
Kéki Sándor,
Szilágyi László Sz.,
Deák György,
Zsuga Miklós
Publication year - 2002
Publication title -
journal of mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 1076-5174
DOI - 10.1002/jms.366
Subject(s) - chemistry , alkali metal , mass spectrometry , desorption , ethylene glycol , selectivity , matrix assisted laser desorption/ionization , ethylene , ion , matrix (chemical analysis) , inorganic chemistry , polymer chemistry , analytical chemistry (journal) , organic chemistry , chromatography , adsorption , catalysis
The cationization of poly(ethylene glycol)s, PEG 4000 and PEG 6000, under matrix‐assisted laser desorption/ionization conditions was studied by using different concentration ratios of the sodium ion, as the reference ion, and another alkali metal ion (Li + , K + , Rb + , Cs + ). A linear correlation was found between the intensity ratio of the sodiated PEGs and PEGs cationized with alkali metal ions versus the initial concentration ratio of sodium and alkali metal ions. The slopes of these straight lines are proposed as a novel selectivity ratio for the ionization process. The intensity distribution of the cationized PEGs was also investigated. It was found that the cationized oligomers follow Poisson statistics. The M n and M w values were also evaluated. An explanation for the observed effects is given. Copyright © 2002 John Wiley & Sons, Ltd.