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Improved ion optics for introduction of ions into a 9.4‐T Fourier transform ion cyclotron resonance mass spectrometer
Author(s) -
Chen Yu,
Leach Franklin E.,
Kaiser Nathan K.,
Dang Xibei,
Ibrahim Yehia M.,
Norheim Randolph V.,
Anderson Gordon A.,
Smith Richard D.,
Marshall Alan G.
Publication year - 2015
Publication title -
journal of mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 1076-5174
DOI - 10.1002/jms.3523
Subject(s) - fourier transform ion cyclotron resonance , chemistry , quadrupole mass analyzer , ion cyclotron resonance , mass spectrometry , ion , hybrid mass spectrometer , ion source , selected ion monitoring , analytical chemistry (journal) , ion trap , quadrupole , atomic physics , cyclotron , physics , tandem mass spectrometry , selected reaction monitoring , chromatography , gas chromatography–mass spectrometry , organic chemistry
Enhancements to the ion source and transfer optics of our 9.4 T Fourier transform ion cyclotron resonance (ICR) mass spectrometer have resulted in improved ion transmission efficiency for more sensitive mass measurement of complex mixtures at the MS and MS/MS levels. The tube lens/skimmer has been replaced by a dual ion funnel and the following octopole by a quadrupole for reduced ion cloud radial expansion before transmission into a mass‐selective quadrupole. The number of ions that reach the ICR cell is increased by an order of magnitude for the funnel/quadrupole relative to the tube lens/skimmer/octopole. Copyright © 2015 John Wiley & Sons, Ltd.