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Practical approaches to the ESI‐MS analysis of catalytic reactions
Author(s) -
Yunker L. P. E.,
Stoddard R. L.,
McIndoe J. S.
Publication year - 2014
Publication title -
journal of mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 1076-5174
DOI - 10.1002/jms.3266
Subject(s) - chemistry , catalysis , mass spectrometry , organic chemistry , combinatorial chemistry , chromatography
Catalytic reactions are almost by necessity a mixture of reactants, products, byproducts, intermediates, resting states and decomposed material. The analysis of such reactions by ESI‐MS produces well‐separated and diagnostic signals for individual components, making it capable of dissecting such mixtures over various time domains and a wide dynamic range. Continuous monitoring allows the dynamics of reactions to be studied in exquisite detail. In this perspective special feature, Scott McIndoe and colleagues present and discuss some of the key aspects and challenges of this unique mass spectrometric application. Scott McIndoe (Professor of Chemistry, University of Victoria, BC, Canada) is one of the leading figures in the use of mass spectrometry to extract mechanistic information from metal‐catalyzed reactions.