Premium
Laser desorption dual spray post‐ionization mass spectrometry for direct analysis of samples via two informative channels
Author(s) -
Liu Jia,
Zhang Chengsen,
Sun Jiamu,
Ren Xinxin,
Luo Hai
Publication year - 2013
Publication title -
journal of mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 1076-5174
DOI - 10.1002/jms.3145
Subject(s) - chemistry , analyte , mass spectrometry , analytical chemistry (journal) , ionization , reagent , ambient ionization , laser , desorption , surface enhanced laser desorption/ionization , chromatography , soft laser desorption , matrix assisted laser desorption electrospray ionization , matrix assisted laser desorption/ionization , sample preparation in mass spectrometry , electrospray ionization , chemical ionization , ion , organic chemistry , adsorption , physics , optics
A laser desorption dual spray post‐ionization mass spectrometry method is described, and its usefulness is demonstrated with the examples of selective detection of food components, manipulation of protein charge state distribution and investigation on the formation of magic number clusters. The method is carried out by adopting two spray emitters for post‐ionization of analytes desorbed by a pulsed infrared laser. Various components in a complex sample or distinct behavior of an analyte in two different spray reagents can be rapidly probed by the method quasi‐simultaneously, highlighting the potential applications of this method for protein characterization, reaction study and food analysis. Copyright © 2013 John Wiley & Sons, Ltd.