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ESI‐MS studies of mixed‐ligand Fe(II) complexes containing 1,10‐phenanthroline and 1,10‐phenanthroline‐5,6‐dione as ligands
Author(s) -
Kobetić Renata,
Gembarovski Dubravka,
Baranović Goran,
Gabelica Vesna
Publication year - 2008
Publication title -
journal of mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 1076-5174
DOI - 10.1002/jms.1372
Subject(s) - chemistry , phenanthroline , ligand (biochemistry) , acetonitrile , electrospray ionization , solvent , denticity , medicinal chemistry , hydrogen bond , mass spectrometry , electrospray , molecule , inorganic chemistry , organic chemistry , metal , chromatography , biochemistry , receptor
In order to monitor the progression of the synthesis and the separation of novel mixed‐ligand iron complexes containing 1,10‐phenanthroline, 1,10‐phenanthroline‐5,6‐dione, and NCS − as ligands all products were mass analyzed by electrospray ionization ion trap MS/MS. The spectra of methanol (MeOH), acetonitrile (ACN), water, and ethanol (EtOH) solutions were collected and the results were compared. It was detected under applied electrospray ionization mass spectrometry (ESI‐MS) conditions that MeOH, water, and EtOH formed solvent clusters around the free or complexed 1,10‐phenanthroline‐5,6‐dione. Owing to the solvent‐ligand hydrogen‐bond formation, the solvent‐ligand clusters were formed in the polar protic solvents. The number of protic solvent molecules per complex ion in cluster depended on the number of 1,10‐phenanthroline‐5,6‐dione ligands in the complex ion. Unlike MeOH, EtOH, or water, ACN was not involved in the formation of the solvent clusters with the iron complexes containing 1,10‐phenanthroline‐5,6‐dione as ligand. We also showed that the NCS − group under certain solvent conditions served as a bidentate ligand. Copyright © 2008 John Wiley & Sons, Ltd.