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Past, present and future of mass spectrometry in the analysis of residues of banned substances in meat‐producing animals
Author(s) -
De Brabander H. F.,
Le Bizec B.,
Pinel G.,
Antignac J.P.,
Verheyden K.,
Mortier V.,
Courtheyn D.,
Noppe H.
Publication year - 2007
Publication title -
journal of mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 1076-5174
DOI - 10.1002/jms.1272
Subject(s) - chemistry , mass spectrometry , residue (chemistry) , human health , anabolism , chromatography , environmental chemistry , biochemistry , environmental health , medicine
A residue is a trace (µg kg −1 , ng kg −1 ) of a substance, present in a matrix. Banned substances, such as growth promoters, which are abused in animal fattening and where this article is focused on, may be divided into four major groups: thyreostats, anabolics or anabolic steroids, corticosteroids and beta‐agonists or repartitioning agents. The combination of chromatographic techniques with mass spectrometry (GC‐MS n , LC‐MS n , etc.) plays a key role in the production of specific results in residue analysis. In this review, the past, present and future of mass spectrometry in this area are discussed in the light of the impact of these substances on human health and the reliable production of analytical results, ready for challenge in a court. Copyright © 2007 John Wiley & Sons, Ltd.