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Solvation of acylium fragment ions in electrospray ionization quadrupole ion trap and Fourier transform ion cyclotron resonance mass spectrometry
Author(s) -
Guan Ziqiang,
Liesch Jerrold M.
Publication year - 2001
Publication title -
journal of mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 1076-5174
DOI - 10.1002/jms.124
Subject(s) - chemistry , fourier transform ion cyclotron resonance , electrospray ionization , mass spectrometry , ion trap , ion , ion cyclotron resonance , adduct , analytical chemistry (journal) , ion source , molecule , acetonitrile , electrospray , quadrupole ion trap , solvation , ionization , mass spectrum , chromatography , organic chemistry , cyclotron
In electrospray ionization (ESI) quadrupole ion trap and Fourier transform ion cyclotron resonance mass spectrometry, certain fragment ions (e.g. acylium ions) generated either during the ion transportation process (in the source interface region) or in the ion trap are found to undergo ion–molecule reactions with ESI solvent molecules (water, acetonitrile and aliphatic alcohols) to form adduct species. These unexpected solvated fragment ions severely complicate the interpretation of mass spectrometic data. High‐resolution accurate mass measurements are important in establishing the elemental compositions of these adduct species and preventing erroneous data interpretation. Copyright © 2001 John Wiley & Sons, Ltd.