Premium
Liquid secondary ion mass spectra and fast atom bombardment mass spectra of diquaternary pyridinium oxime salts
Author(s) -
Kunkel Gary J.,
Busch Kenneth L.,
Dunphy Richard,
Burinsky David J.,
Barak Ruth,
Bel Peter,
Amitai Gabriel,
Vincze Adam
Publication year - 1995
Publication title -
journal of mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 1076-5174
DOI - 10.1002/jms.1190300209
Subject(s) - chemistry , mass spectrum , pyridinium , fast atom bombardment , ion , protonation , deprotonation , oxime , mass spectrometry , hydrogen atom , photochemistry , medicinal chemistry , organic chemistry , alkyl , chromatography
Positive‐ion mass spectra of diquaternary pyridinium oxime salts were measured using fast atom bombardment and liquid secondary ion mass spectrometry in different laboratories to establish both the characteristic behavior and the spectral variability of this class of compounds. Molecular ions observed in these mass spectra include the one‐electron reduced doubly charged cation, the deprotonated double charged cation and the anion‐reduced doubly charged cation. Common fragment ions include the products of simple cleavages along the aliphatic bridge between the heterocyclic rings. Concomitant loss of hydrogen and cyclization of the bridge can occur, along with losses of OH, NOH and CHNOH from various fragment ions. A nitrobenzyl alcohol matrix generally gave superior results to glycerol and thioglycerol in all laboratories, although the use of additive surfactant acids such as p ‐toluenesulfonic acid or camphorsulfonic acid in glycerol could provide useful results.