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Characterization of acylcarnitines using fast atom bombardment mass spectrometry and gas chromatography/mass spectrometry
Author(s) -
Van Bocxlaer J. F.,
Claeys M.,
Van Den Heuvel H.,
De Leenheer A. P.
Publication year - 1995
Publication title -
journal of mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 1076-5174
DOI - 10.1002/jms.1190300112
Subject(s) - chemistry , mass spectrometry , fast atom bombardment , electron ionization , chromatography , chemical ionization , gas chromatography , gas chromatography–mass spectrometry , ionization , analytical chemistry (journal) , direct electron ionization liquid chromatography–mass spectrometry interface , mass , mass spectrum , ion , organic chemistry
Mass spectral data are reported for an extended series of synthesized acylcarnitines. Direct mass spectrometry was performed using ionization by fast atom bombardment in combination with high‐energy collisional activation and B / E linked scanning. The data show that it is possible to distinguish between isomeric compounds using this technique. Gas chromatographic/mass spectrometric analysis data for acylcarnitines, as their acyloxylactone derivatives, are reported. Both electron impact and chemical ionization modes were used, permitting the unequivocal characterization and identification of the various compounds. In view of the recent marked increase in acylcarnitine profiling activities, the comprehensively reported mass spectrometric and gas chromatographic data may be useful for reference purposes.