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Conformal orbit sparing radiation therapy: a treatment option for advanced skin cancer of the parotid and ear region
Author(s) -
Foley Heath,
Hopley Shane,
Brown Elizabeth,
Bernard Anne,
Foote Matthew
Publication year - 2016
Publication title -
journal of medical radiation sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.484
H-Index - 18
eISSN - 2051-3909
pISSN - 2051-3895
DOI - 10.1002/jmrs.161
Subject(s) - medicine , radiation therapy , radiation treatment planning , dosimetry , nuclear medicine , orbit (dynamics) , radiology , engineering , aerospace engineering
New surgical methods have enabled resection of previously in‐operable tumours in the region of the parotid gland and ear. This has translated to deeper target volumes being treated with adjuvant radiotherapy. Due to the limitations of existing conformal techniques, alternative planning approaches are required to cover the target volume with appropriate sparing of adjacent critical structures. Although intensity modulated radiation therapy ( IMRT ) may be able to achieve these goals compared with the existing conformal method, a new orbital sparing radiation therapy ( OSR aT) technique was evaluated as an alternative conformal planning process. The study objective was to evaluate the dosimetry of three planning methods: pre‐existing conformal, IMRT and OSR aT techniques. Methods Ten patients were planned retrospectively using the existing three‐dimensional conformal radiotherapy (3 DCRT ), IMRT and OSR aT techniques. Dosimetry was analysed using the homogeneity index ( HI ), conformity index ( CI ), the volume of planning target volumes ( PTV ) under and over treated by the 95% isodose and dose to critical structures. Results OSR aT achieved superior 95% coverage of the high‐dose PTV while delivering HI similar to IMRT for intermediate and high‐dose PTV s. The CI for the high‐dose PTV was comparable between the three techniques, however IMRT was statistically better for the low‐ and intermediate dose PTV s. All three techniques showed adequate orbital sparing, however OSR aT and IMRT achieved this with less under dosing of the PTV s. Conclusion For the treatment of patients with advanced skin cancer of the parotid and ear, both IMRT and the OSR aT techniques are viable options.

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