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Reference Values for Pediatric Atrial Volumes Assessed by Steady‐State Free‐Precession Magnetic Resonance Imaging Using Monoplane and Biplane Area‐Length Methods
Author(s) -
Voges Inga,
Caliebe Amke,
Hinz Sophia,
Boroni Grazioli Simona,
Gabbert Daniel Dominik,
Wegner Philip,
Uebing Anselm Sebastian,
Daubeney Piers E. F.,
Pennell Dudley J.,
Krupickova Sylvia
Publication year - 2023
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.28230
Subject(s) - biplane , nuclear medicine , medicine , magnetic resonance imaging , cardiology , mathematics , radiology , engineering , aerospace engineering
Background Measurement of atrial volumes by MRI is becoming increasingly important in pediatric cardiac disorders. However, MRI normal values for atrial volumes in children are lacking. Purpose To establish pediatric reference values for atrial volumes. Study Type Retrospective. Subjects A total of 155 healthy children from two large institutions (103 male, age 13.9 ± 2.8 years, range 4–18 years). Field Strength/Sequence A 1.5 T; balanced steady‐state free precession (bSSFP) sequence. Assessment The monoplane and biplane area‐length methods were used to measure minimal and maximal left and right atrial volumes (LA min , LA max , RA min , and RA max ) from four‐chamber (4ch) and two‐chamber (2ch) MR cine images. Centile charts and tables for atrial volumes were created. Statistical Tests Descriptive statistics, lambda‐mu‐sigma (LMS)‐method of Cole and Green, univariable and multivariable linear regression models. A P value < 0.05 was considered to be statistically significant. Results In the multivariable linear model, body surface area was significantly associated with all atrial volumes and sex was significantly associated with RA volumes, LA volumes measured in the 2ch‐view as well as biplane LA max. Average atrial volumes measured: monoplane 4ch: LA min 13.1 ± 4.8 mL/m 2 , LA max 33.4 ± 8.8 mL/m 2 , RA min 18.5 ± 6.8 mL/m 2 , RA max 33.2 ± 9.6 mL/m 2 ; monoplane 2ch: LA min 12.7 ± 4.9 mL/m 2 , LA max 30.5 ± 9.5 mL/m 2 ; biplane: LA min 12.3 ± 4.5 mL/m 2 , LA max 30.9 ± 8.7 mL/m 2 . Data Conclusion Pediatric MRI reference values for atrial volumes have been provided. Technical Efficacy 2 Evidence Level 4