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Quantitative Susceptibility Mapping: Technical Considerations and Clinical Applications in Neuroimaging
Author(s) -
Vinayagamani Selvadasan,
Sheelakumari R,
Sabarish Sekar,
Senthilvelan Santhakumar,
Ros Roopa,
Thomas Bejoy,
Kesavadas Chandrasekharan
Publication year - 2021
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.27058
Subject(s) - quantitative susceptibility mapping , neuroimaging , magnetic resonance imaging , biomarker , medicine , neuroscience , computer science , radiology , psychology , biology , biochemistry
Quantitative susceptibility mapping (QSM) is a novel magnetic resonance imaging (MRI) technique for quantifying the spatial distribution of magnetic susceptibility within an object or tissue. Recently, QSM has been widely used to study various dominant magnetic susceptibility sources in the brain, including iron and calcium. In addition, the method enables mapping of the cerebral metabolic rate of oxygen, which could act as a new metabolic biomarker for diseases that involve disruption of the brain's oxygen supply. Thus, the clinical applications of QSM are wide‐reaching and hold great promise as imaging biomarkers for studying several neurological diseases. This review aims to summarize the physical concepts and potential clinical applications of QSM in neuroimaging. Evidence Level 5 Technical Efficacy Stage 2