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Applications of PET‐MRI in musculoskeletal disease
Author(s) -
Kogan Feliks,
Broski Stephen M.,
Yoon Daehyun,
Gold Garry E.
Publication year - 2018
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.26183
Subject(s) - musculoskeletal disease , medicine , modality (human–computer interaction) , magnetic resonance imaging , disease , radiology , pathology , computer science , artificial intelligence
New integrated PET‐MRI systems potentially provide a complete imaging modality for diagnosis and evaluation of musculoskeletal disease. MRI is able to provide excellent high‐resolution morphologic information with multiple contrast mechanisms that has made it the imaging modality of choice in evaluation of many musculoskeletal disorders. PET offers incomparable abilities to provide quantitative information about molecular and physiologic changes that often precede structural and biochemical changes. In combination, hybrid PET‐MRI can enhance imaging of musculoskeletal disorders through early detection of disease as well as improved diagnostic sensitivity and specificity. The purpose of this article is to review emerging applications of PET‐MRI in musculoskeletal disease. Both clinical applications of malignant musculoskeletal disease as well as new opportunities to incorporate the molecular capabilities of nuclear imaging into studies of nononcologic musculoskeletal disease are discussed. Lastly, we discuss some of the technical considerations and challenges of PET‐MRI as they specifically relate to musculoskeletal disease. Level of Evidence 5 Technical Efficacy Stage 3 J. Magn. Reson. Imaging 2018;48:27–47.