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Reference values of cardiac ventricular structure and function by steady‐state free‐procession MRI at 3.0T in healthy adult chinese volunteers
Author(s) -
Lei Xiaolin,
Liu Hong,
Han Yuchi,
Cheng Wei,
Sun Jiayu,
Luo Yong,
Yang Dan,
Dong Yang,
Chung Yiochu,
Chen Yucheng
Publication year - 2017
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.25520
Subject(s) - ejection fraction , medicine , cardiology , body surface area , steady state free precession imaging , magnetic resonance imaging , ventricle , cardiac magnetic resonance imaging , population , heart failure , radiology , environmental health
Purpose To establish normal reference values of left ventricular (LV) and right ventricular (RV) dimension, volume, mass, and ejection fraction in a Chinese population using cardiac magnetic resonance imaging (MRI). Materials and Methods A total of 120 (60 males; 60 females; 23–83 years) healthy Han Chinese subjects without cardiovascular disease or risk factors were recruited. They underwent comprehensive MRI examination at 3.0T. LV/RV morphology and function were evaluated by steady‐state free‐procession (SSFP) sequence. Parameters were analyzed according to a standard postprocessing protocol. Results Significant differences in LV size, mass, volume, and ejection fraction (EF) between sexes were noted (all P < 0.05). After indexing using body surface area (BSA), LV end‐diastolic volume (EDV), and LV mass index were greater in males than in females (76.5 vs. 68.7 mL/m[2][Pattynama PM, 1993], P < 0.001; 52.9 vs. 45.1 g/m[2][Pattynama PM, 1993], P < 0.001; respectively). LVEF was lower in males than in females (64.6% vs. 67.1%, P = 0.007, respectively). RV volume was higher and RVEF lower in males compared with females (75.3 vs. 62.7 mL/m[2][Pattynama PM, 1993], P < 0.001; 59.9% vs. 62.6%, P = 0.001, respectively). Age was associated significantly with indices of LV and RV volume in females (left ventricular end‐diastolic volume index: r = −0.41 P = 0.001; left ventricular end‐systolic volume index: r = −0.37 P = 0.004; left ventricular end‐diastolic volume index: r = −0.53 P < 0.001; right ventricular end‐systolic volume index: r = −0.43 P < 0.001), but not in males (all P > 0.05). Conclusion These data suggest that sex and age affect ventricular parameters in healthy Han Chinese subjects without cardiovascular disease or risk factors. Level of Evidence : 2 Technical Efficacy : Stage 2 J. MAGN. RESON. IMAGING 2017;45:1684–1692