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Fat‐suppressed T 2 mapping of femoral cartilage in the porcine knee joint: A comparison with conventional T 2 mapping
Author(s) -
Ryu Young Jin,
Hong Sung Hwan,
Kim Hyeonjin,
Choi JaYoung,
Yoo Hye Jin,
Kang Yusuhn,
Park Sang Joon,
Kang Heung Sik
Publication year - 2017
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.25430
Subject(s) - intraclass correlation , anatomy , sagittal plane , magnetic resonance imaging , osteoarthritis , articular cartilage , cartilage , nuclear medicine , medicine , condyle , reproducibility , chemistry , pathology , radiology , alternative medicine , chromatography
Purpose To investigate the effect of fat suppression on T 2 mapping of the articular cartilage in the porcine knee joint using magnetic resonance imaging (MRI). Materials and Methods Eleven porcine knee joints were harvested en bloc with intact capsules. We performed T 2 mapping of the articular cartilage in the medial femoral condyle at 3T either with (fat‐suppressed T 2 mapping) or without (conventional T 2 mapping) fat suppression in the sagittal plane under two frequency‐encoding directions: from superior to inferior (SI) and inferior to superior (IS). Two observers measured the T 2 values of the medial femoral condyle cartilage in four regions: in the anterior oblique, central horizontal, posterior oblique, and posterior vertical portions. We evaluated reproducibility of the fat‐suppressed and conventional T 2 mapping by changing the frequency‐encoding direction. Results The mean T 2 values of fat‐suppressed T 2 mapping were significantly lower than those of conventional T 2 mapping for five of eight comparisons ( P < 0.017). The mean T 2 values between fat‐suppressed T 2 ‐SI and fat‐suppressed T 2 ‐IS did not differ significantly in any region ( P = 0.077–0.873). However, the mean T 2 values of conventional T 2 ‐SI were significantly lower compared with conventional T 2 ‐IS in three of the regions ( P < 0.05). The intraclass correlation coefficient (ICC) between the two fat‐suppressed T 2 maps was higher than the ICC between the two conventional T 2 maps (0.276–0.800 vs. –0.032–0.455) for three regions. Conclusion Compared with conventional T 2 mapping, fat‐suppressed T 2 mapping provides lower T 2 values of the articular cartilage and more reproducible results for the porcine knee joint. Level of Evidence: 2 J. Magn. Reson. Imaging 2017;45:1076–1081