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Patient adaptive maximal resolution magnetic resonance myocardial stress perfusion imaging
Author(s) -
Ripley David P.,
McDiarmid Adam K.,
Kidambi Ananth,
Uddin Akhlaque,
Swoboda Peter P.,
Musa Tarique A.,
Erhayiem Bara,
Bainbridge Gavin J.,
Greenwood John P.,
Plein Sven,
Higgins David M.
Publication year - 2015
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.24846
Subject(s) - magnetic resonance imaging , perfusion , nuclear magnetic resonance , medicine , myocardial perfusion imaging , cardiac magnetic resonance , radiology , cardiology , nuclear medicine , physics
Purpose To demonstrate the feasibility of an automatic adaptive acquisition sequence. Magnetic resonance perfusion pulse sequences often leave potential acquisition time unused in patients with lower heart‐rates (HR) and smaller body size. Materials and Methods A perfusion technique was developed that automatically adapts to HR and field‐of‐view by maximizing in‐plane spatial resolution while maintaining temporal resolution every cardiac cycle. Patients ( n = 10) and volunteers ( n = 10) were scanned with both a standard resolution and adaptive method. Image quality was scored, signal‐to‐noise ratio (SNR) calculated, and width of dark‐rim artifact (DRA) measured. Results The acquired spatial resolution of the adaptive sequence (1.92 × 1.92 mm 2 ± 0.34) was higher than the standard resolution (2.42 × 2.42 mm 2 ) ( P < 0.0001). Mean DRA width was reduced using the adaptive pulse sequence (1.94 ± 0.60 mm vs. 2.82 ± 0.65 mm, P < 0.0001). The signal‐to‐noise ratio (SNR) was higher with the standard pulse sequence (6.7 ± 2.2 vs. 3.8 ± 1.8, P < 0.0001). There was no difference in image quality score between sequences in either volunteers (1.1 ± 0.31 vs. 1.0 ± 0.0, P = 0.34) or patients (1.3 ± 0.48 vs. 1.3 ± 0.48, P = 1.0). Conclusion Optimizing the use of available imaging time during first‐pass perfusion with a magnetic resonance imaging pulse sequence that adapts image acquisition duration to HR and patient size is feasible. Acquired in‐plane spatial resolution is improved, the DRA is reduced, and while SNR is reduced with the adaptive sequence consistent with the lower voxel size used, image quality is maintained. J. Magn. Reson. Imaging 2015;42:946–953.